Tekho Marine Biotech Co., Ltd.

【TPF 2.0 Version】Totipotent Prostembryona Factor® lyophilized powder ampoule

Calling this active ingredient “a game-changer in efficacy and claims,” jurors singled out its “amazing patents and incredibly innovative technology.” The active ingredient - Totipotent Prostembryona Factor® – is derived from embryonic stem cells from the fertilized roes of deep-sea fish, via multiple low-temperature patented extraction processes. The fertilized roe is extracted without having to kill any female fish, which impressed the panel. Within the ingredients are natural complex peptides – including exosomes, growth factors, and cytokines – and it has obtained its own INCI name and patents in the U.S., Japan, and the Taiwan region. There are several versions of the ingredient for different applications: TPF -TPF-H01, which can be used as a functional dressing to promote the healing of burns, scalds, and skin wounds; TPF-EX05, a raw material for functional cosmetics and hair health, to moisturize, brighten, delay skin aging, and promote hair growth and hair density; and TPF-101, a functional food ingredient, which can increase the concentration of IGF-1, or insulin-like growth factor in the blood, and reduce the concentration of ACE, or angiotensin-converting enzyme, said to delay aging. The panel liked that this ingredient could bring “innovation” to beauty products and noted that “mixing medicine products with cosmetics is always welcome.”

Booth#: 10-P05

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Product Headline
Calling this active ingredient “a game-changer in efficacy and claims,” jurors singled out its “amazing patents and incredibly innovative technology.” The active ingredient - Totipotent Prostembryona Factor® – is derived from embryonic stem cells from the fertilized roes of deep-sea fish, via multiple low-temperature patented extraction processes. The fertilized roe is extracted without having to kill any female fish, which impressed the panel. Within the ingredients are natural complex peptides – including exosomes, growth factors, and cytokines – and it has obtained its own INCI name and patents in the U.S., Japan, and the Taiwan region. There are several versions of the ingredient for different applications: TPF -TPF-H01, which can be used as a functional dressing to promote the healing of burns, scalds, and skin wounds; TPF-EX05, a raw material for functional cosmetics and hair health, to moisturize, brighten, delay skin aging, and promote hair growth and hair density; and TPF-101, a functional food ingredient, which can increase the concentration of IGF-1, or insulin-like growth factor in the blood, and reduce the concentration of ACE, or angiotensin-converting enzyme, said to delay aging. The panel liked that this ingredient could bring “innovation” to beauty products and noted that “mixing medicine products with cosmetics is always welcome.”
Product Description​
Active Ingredient Totipotent Prostembryona Factor® ‧Derived from precious deep-sea fish fertilized roes (embryonic stem cells) through multiple low-temperature patented extraction processes. ‧Natural complex peptides (exosomes, growth factors, cytokines) that has successfully obtained INCI NAME, and the invention patent of USA, Japan, Taiwan. ‧Various tests have confirmed TPF has excellent efficacy when used in the fields of beauty care, hair health, functional food and medical dressings. ‧Nano-sized composite ingredient that can be completely absorbed. ‧Adopts pharmaceutical grade ultra-low temperature vacuum freeze-dried technology, without added preservatives, has convenient storage and transportation functions and ensures optimal biological activity.
Claims & Benefits
Application of functional TPF -TPF-H01 (functional dressing) ◆Promote the healing of burns, scalds and skin wounds. -TPF-EX05 (Functional Cosmetics & Hair-Health Raw Material) ◆Comprehensive repair effects such as moisturizing, brightening, and delaying skin aging. ◆ Effectively promote hair growth and hair density. -TPF-101 (Functional Food Ingredient) ◆Effectively increase the concentration of IGF-1 (insulin-like growth factor) in blood. ◆Effectively reduce the concentration of ACE (angiotensin-converting enzyme) in blood. ◆Helps body growth and delays aging. ◆Recognized by the Food and Drug Administration of the Ministry of Health and Welfare in Taiwan as an edible food ingredient.
Technical Details​
Active Ingredient Totipotent Prostembryona Factor® (TPF) INCI name: Fertilzied Roe Extract (No.33531). Packaging materials: Lyophilized powder (original solution) with ampoule. The raw material, Totipotent Prostembryona Factor® (TPF), is manufactured by Tekho Marine Biotech Co., Ltd. and its details are as follows. -INCI Name: Fertilized Roe Extract Origin / Process: Taiwan / grouper Ratio (%): 93% -INCI Name: Manntol Origin / Process:Taiwan / (NON-GMO vegetable) Ratio (%): 5% -INCI Name: Trehalose Origin / Process: Thailand / (NON-GMO cassava) Ratio (%): 2%
Launch Date
03/30/2024
Price List, Target Consumer & Market Segments
Target customer: Medical aesthetic grade, mid- to high-priced product development, focusing on repair, regeneration and anti-aging products. Price List: TPF-EX05 Lyophilized Powder 10ml*5 vials/box US$80 TPF-EX05 Lyophilized Powder 50ml*5 vials/box US$365
Website and Social Channel/s
Company official website: http://www.tekho.com.tw/ TPF’s brand Bioyona official website: https://www.bioyona.com.tw/
What sets your product apart and why is it innovative?
The first company in the world to use "fertilized" roe extract as cosmetic products. (INCI name: Fertilzied Roe Extract No.33531) ◆T: Totipotent means the highest level of stem cell (pluripotent, multipotent, single function) ◆P: Pro=super, stem=stem cell, embryona=embryonic ◆F: Factor TPF is extracted from precious deep-sea fish fertilized roes (embryonic stem cells) through biotechnology. Our advantage is that we have our own fish farm, so we control the source of the raw materials, and we are not afraid that the raw materials will be out of stock. And the composition and function of exosomes is the first and the best choice in cosmetic industry. Because exosomes depend on the source cell, mainly promotes tissue repair and regeneration, TPF is totipotent meaning the biocompatibility with human being is the best as well. Better than plant stem cell, roe extract, and safer than mammal stem cell (risk of zoonosis) and human stem cell (infectious disease and ethics). No specific zoonosis associated with fish in history and it is exclusive at market visibility.
How do you promote your product on multiple channels?​
Count on the offline face-to-face service and promotion of medical beauticians. Professional skin care technology helps post-operative customers perform repair treatments by using Bioyona, which main ingredient is TPF. Especially the highest concentration of TPF ampoule, also sunscreen and face mask. Social media through Bioyona brand such as Instagram, Facebook, Tiktok, Youtube and 小紅書 to promote TPF remarkable efficacy. Ask influencer to talk about TPF and introduce more in the beauty market, let everyone knows its innovative ingredient. If the customers has their own brand, they can also purchase TPF for OEM use.
How does your product meet the evaluation criteria of its category?​
TPF ingredient is definitely the most innovative and original in the world. None of the company use it as an ingredient before, we are the first one. In addition to the boss’s professional medical background, TPF also arranges the certification of invention patents in many countries to create extraordinary cosmetic raw materials. Using our strong foundation in aquaculture and fisheries, we have transformed into biotechnology, an exclusive patented technology combined with R&D to create such high-quality products TPF for everyone to share all over the world. We take care of your well-being inside out, from skin to scalp and health, from outer to inner. Start your journey with the essence of deep-sea wonders. Let's begin the extraordinary journey now.
Patents
Obtained the patent of Totipotent Prostembryona Factor® and approved by INCI Name No.33531. Obtained TPF Japanese INCI name by JCIA No.21098. Obtained the United States patent invention of Totipotent Prostembryona Factor®: Medical composition for promoting skin wound healing and its use Patent No.US010821137B2. Obtained Taiwan Invention Patent: Compositions for use in wound healing and method of use therefor. Invention Patent No.I729355. Obtained Japan patent invention of Totipotent Prostembryona Factor® : Medical composition for promoting skin wound healing and its use Patent No.6912830. Obtained Taiwan Invention Patent (TPF-88™): method of using fish fertilized roe extract to manufacture hair growth composition.
What is you brand commitment to sustainability, ethical practices, and social responsibility? Please describe.
We are a friendly biological factory that is consistent with sustainable use and environmental protection. We don't need to kill any female fish to obtain fertilized roes, different from common inactive roe extract or caviar. Professionally extract the most essence within the golden eight hours and use it as cosmetic raw materials. Utilize the natural complex peptides (exosomes, growth factors, cytokines) to create a new era in the skin care industry.
Certifications
Obtained the patent of Totipotent Prostembryona Factor® and approved by INCI Name No.33531. Obtained TPF Japanese INCI name by JCIA No.21098. Obtained the United States patent invention of Totipotent Prostembryona Factor®: Medical composition for promoting skin wound healing and its use Patent No.US010821137B2. Obtained Taiwan Invention Patent: Compositions for use in wound healing and method of use therefor. Invention Patent No.I729355. Obtained Japan patent invention of Totipotent Prostembryona Factor® : Medical composition for promoting skin wound healing and its use Patent No.6912830. Obtained Taiwan Invention Patent (TPF-88™): method of using fish fertilized roe extract to manufacture hair growth composition. 2020 Gold Quality Award of Monde Selection 2020-TPF Skin Activating Treatment Serum 2022 Won SNQ (Symbol of national Quality) Guaranteed Recommended-Royal Roe Peptide Capsule (Queen / Women Formula) 2023 Finalist for 'Best New Serum' in the Pure Beauty Global Awards 2023-Bioyona Skin Activating Treatment Serum Ampoule Shortlisted in COSMO TRENDS 2023 Nip-Tuck Relief - Bioyona Skin Activating Treatment Serum Ampoule

Timeline

18 July 2024

Platform Opening

30 September 2024

Entries closing

21 October 2024

Finalists Announcement

13 November 2024

Awards Ceremony
Winners Announcement

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